Description

2-(Triphenylphosphoranylidene)Malonic Acid Dimethyl Ester is a specialized Wittig-Horner reagent, a key building block in organic synthesis. This compound matters for its crucial role in facilitating the stereoselective formation of alkenes and other complex molecular frameworks. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for the stereoselective construction of alkenes and α,β-unsaturated esters, key motifs in many drug molecules.
• Agrochemical Production: Used in the synthesis of complex organic molecules for crop protection agents and pesticides.
• Advanced Material Research: Serves as a precursor in the development of organic semiconductors, liquid crystals, and specialty polymers.
• Academic & Industrial R&D: A fundamental tool in organic chemistry laboratories for method development and the synthesis of novel compounds.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	2-(Triphenylphosphoranylidene)Malonic Acid Dimethyl Ester
CAS No.	19491-23-7
Molecular Formula	C23H21O4P
Molecular Weight	392.38 g/mol
Synonyms	Dimethyl (Triphenylphosphoranylidene)malonate; Dimethyl 2-(Triphenylphosphoranylidene)malonate; (Triphenylphosphoranylidene)malonic Acid Dimethyl Ester; Malonic Acid, 2-(Triphenylphosphoranylidene)-, Dimethyl Ester; Wittig-Horner Reagent for Malonate; Phosphonium, (2,2-Dimethoxy-2-oxoethylidene)triphenyl-, Inner Salt
EINECS	243-108-8

Quality Control

Our 2-(Triphenylphosphoranylidene)Malonic Acid Dimethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is analyzed via modern analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	142 - 148 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.