Description

2-Bromopropionitrile is a versatile halogenated nitrile building block used extensively in organic synthesis. Its high reactivity, particularly as an alkylating agent and precursor to various heterocycles, makes it a critical intermediate for advanced chemical manufacturing. This compound is essential for researchers and industrial chemists in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyanoethyl or bromoalkyl motifs.
• Agrochemical Synthesis: Used as a precursor for herbicides, fungicides, and plant growth regulators.
• Heterocyclic Chemistry: Valuable reagent for the construction of pyrimidines, pyridines, and other nitrogen-containing heterocycles.
• Polymer Modification: Serves as a functional monomer or cross-linking agent in specialty polymer production.
• Chemical Research: Employed in organic methodology development as an electrophile for C-C and C-N bond-forming reactions.
• Ligand and Catalyst Preparation: Intermediate in the synthesis of complex ligands for catalytic systems.

Basic Information

Product Name	2-Bromopropionitrile
CAS No.	19481-82-4
Molecular Formula	C₃H₄BrN
Molecular Weight	133.97 g/mol
Synonyms	2-Bromopropanenitrile; α-Bromopropionitrile; Bromopropiononitrile; Propionitrile, 2-bromo-; NSC 9375; 2-Bromoethyl cyanide (common misnomer); (RS)-2-Bromopropionitrile
EINECS	243-099-8

Quality Control

Our 2-Bromopropionitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The product is sensitive to light and moisture; containers should be kept sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Refractive Index (n20D)	1.480 - 1.490
Density (20°C)	1.60 - 1.65 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.