Description

1-tert-Butyl-4,4'-Difluorocyclohexane is a specialized fluorinated cyclohexane derivative characterized by its tert-butyl and difluoro substituents. This compound serves as a valuable intermediate and building block in advanced organic synthesis, particularly for introducing sterically hindered, fluorinated motifs into target molecules. It is primarily utilized by pharmaceutical, agrochemical, and materials science research and development teams seeking to modulate the physical and biological properties of novel compounds.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where fluorination can enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Research: Serves as a key precursor in developing novel herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Acts as a fluorinated component in the production of advanced electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Science: Employed as a monomer or modifier to create specialty polymers with unique thermal, chemical, or surface properties.
• Chemical Synthesis Building Block: Provides a rigid, fluorinated core structure for constructing complex molecules in medicinal and materials chemistry.
• Catalyst & Ligand Development: Used in the design of novel organometallic catalysts and ligands for asymmetric synthesis.

Basic Information

Product Name	1-tert-Butyl-4,4'-Difluorocyclohexane
CAS No.	19422-34-5
Molecular Formula	C10H18F2
Molecular Weight	176.25 g/mol
Synonyms	4-(tert-Butyl)-1,1-difluorocyclohexane; 1,1-Difluoro-4-tert-butylcyclohexane; 4-tert-Butyl-1,1-difluorocyclohexane; Cyclohexane, 1,1-difluoro-4-(1,1-dimethylethyl)-; 1-tert-Butyl-1,1-difluorocyclohexane; 4-(1,1-Dimethylethyl)-1,1-difluorocyclohexane
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-4,4'-Difluorocyclohexane is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for production where required for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.