Description

(2S)-2-Amino-n-Hydroxy-4-(Methylsulfanyl)Butanamide is a high-purity chiral building block and a key intermediate in organic synthesis. Its value lies in its unique structure, which incorporates both a hydroxamic acid moiety and a methylthio group, making it a versatile precursor for the development of novel bioactive compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on creating enzyme inhibitors, metalloprotease modulators, and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel drug candidates, especially those targeting metalloenzymes.
• Enzyme Inhibitor Synthesis: Serves as a core structure for designing potent inhibitors of matrix metalloproteinases (MMPs), histone deacetylases (HDACs), and other zinc-dependent enzymes.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides that require specific chiral configurations for optimal activity.
• Bioconjugation & Probe Development: The hydroxamic acid group is utilized for chelating metal ions, making it useful in creating diagnostic probes and bioconjugation reagents.
• Chemical Biology Tool: Employed in academic and industrial research to study protein function and develop chemical probes for biological pathways.
• Fine Chemical Synthesis: A valuable building block for the multi-step synthesis of complex, high-value organic molecules in contract research and manufacturing (CRAM) settings.

Basic Information

Product Name	(2S)-2-Amino-n-Hydroxy-4-(Methylsulfanyl)Butanamide
CAS No.	19253-87-3
Molecular Formula	C5H12N2O2S
Molecular Weight	164.22 g/mol
Synonyms	L-2-Amino-N-hydroxy-4-(methylthio)butyramide; L-AHMB; (S)-2-Amino-N-hydroxy-4-(methylthio)butanamide; L-2-Amino-4-(methylthio)butyrohydroxamic acid; NSC 339313; AHMB; L-Butanamide, 2-amino-N-hydroxy-4-(methylthio)-, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-n-Hydroxy-4-(Methylsulfanyl)Butanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.