Description

Dextrorphan -D-o-Glucuronide CAS NO 19153-87-8 is a high-purity, chemically defined metabolite of dextrorphan, formed via glucuronidation. This compound is of significant value as a critical reference standard and analytical reagent in advanced pharmaceutical research and development. It is primarily needed by pharmaceutical companies, contract research organizations (CROs), and analytical laboratories for applications in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and clinical research.

Application

• Primary use as a certified reference standard for the quantification of dextrorphan metabolites in biological matrices.
• Essential reagent in drug metabolism and pharmacokinetic (DMPK) studies to understand metabolic pathways.
• Critical component for the development and validation of bioanalytical methods using LC-MS/MS or HPLC.
• Used in clinical research and toxicology studies to monitor drug exposure and metabolite profiles.
• Supports pharmaceutical R&D for drugs where dextrorphan is a primary or secondary metabolite.
• Application in quality control laboratories for ensuring the accuracy of metabolic assays.

Basic Information

Product Name	Dextrorphan -D-o-Glucuronide
CAS No.	19153-87-8
Molecular Formula	C23H29NO8
Molecular Weight	447.48 g/mol
Synonyms	Dextrorphan Glucuronide; Dextrorphan D-Glucuronide; (+)-3-Hydroxy-N-methylmorphinan Glucuronide; Dextrorphan β-D-Glucuronide; Dextrorphan O-β-D-Glucuronide; Dextrorphan-3-O-β-D-Glucuronide; Ro 1-6794 Glucuronide; Dextrorphan Metabolite
EINECS	Contact for details

Quality Control

Every batch of Dextrorphan -D-o-Glucuronide is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for reference materials. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by validated methods (e.g., HPLC, NMR) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.