Description

(2R,3R,4R,5S)-6-Methylaminohexane-1,2,3,4,5-Pentol, 2-[2,4,6-Triiodo-3 ,5-Bis(Methylcarbamoyl)Phenoxy]Pentanoic Acid is a high-purity, iodinated organic compound primarily used as a key intermediate in advanced diagnostic imaging. This compound matters for its critical role in the synthesis of modern, low-osmolality X-ray contrast media, which are essential for safer and more effective medical imaging procedures. Pharmaceutical manufacturers and fine chemical suppliers in the global healthcare sector require this precise intermediate to ensure the quality and efficacy of their final contrast agent formulations.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of non-ionic, iodinated X-ray contrast agents like Iopamidol, Iohexol, and Ioversol.
• Diagnostic Imaging: Enables the production of contrast media used in computed tomography (CT), angiography, urography, and myelography.
• Research & Development: Serves as a reference standard and starting material for developing new generations of contrast media with improved safety profiles.
• Fine Chemical Synthesis: Used in specialized organic synthesis for creating complex, multi-functional molecules with specific stereochemistry.
• GMP Manufacturing: Supplied to certified facilities for the production of active pharmaceutical ingredients (APIs) under strict regulatory guidelines.

Basic Information

Product Name	(2R,3R,4R,5S)-6-Methylaminohexane-1,2,3,4,5-Pentol, 2-[2,4,6-Triiodo-3 ,5-Bis(Methylcarbamoyl)Phenoxy]Pentanoic Acid
CAS No.	19080-48-9
Molecular Formula	C17H22I3N3O9
Molecular Weight	777.08 g/mol
Synonyms	Iopamidol Intermediate; Iohexol Related Compound; 5-[N-Methylacetamido]-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide precursor; (2R,3R)-2-[[(2R,3S)-2,3-Dihydroxy-3-[(2S,3R,4R,5S)-3,4,5,6-tetrahydroxy-1-methylaminohexyl]propoxy]carbonyl]-3,5-bis(iodomethylcarbamoyl)-4,6-diiodobenzene-1-carboxylic acid; Ioversol Impurity; Non-ionic Contrast Media Intermediate; Iodinated Benzene Derivative
EINECS	Contact for details

Quality Control

Our (2R,3R,4R,5S)-6-Methylaminohexane-1,2,3,4,5-Pentol, 2-[2,4,6-Triiodo-3 ,5-Bis(Methylcarbamoyl)Phenoxy]Pentanoic Acid is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Production adheres to ICH Q7 guidelines, and the material is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 10 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.