Description

2-[(4-Fluorophenyl)Methylideneamino]-3-Phenyl-Propan-1-Ol is a specialized organic intermediate featuring a fluorinated aromatic system and an amino alcohol backbone, making it a valuable synthon for constructing complex molecular architectures. This compound is critical for research and development in advanced pharmaceutical and agrochemical synthesis, where the introduction of fluorine atoms and specific chiral centers is often required to modulate biological activity and metabolic stability. It is primarily sought after by fine chemical manufacturers and R&D laboratories engaged in the development of novel active ingredients, particularly in medicinal chemistry for central nervous system (CNS) and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological disorders and inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorophenyl group enhances lipophilicity and target binding.
• Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis, crucial for producing enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or additive in the development of specialty polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	2-[(4-Fluorophenyl)Methylideneamino]-3-Phenyl-Propan-1-Ol
CAS No.	19064-57-4
Molecular Formula	C16H16FNO
Molecular Weight	257.30 g/mol
Synonyms	2-[(4-Fluorobenzylidene)amino]-3-phenyl-1-propanol; 1-Propanol, 2-[(4-fluorophenyl)methylene]amino]-3-phenyl-; 2-[(4-Fluorobenzylidene)amino]-3-phenylpropan-1-ol; 3-Phenyl-2-[(4-fluorobenzylidene)amino]-1-propanol; (RS)-2-[(4-Fluorobenzylidene)amino]-3-phenylpropan-1-ol; 19064-57-4; 4-Fluoro-N-(1-hydroxy-3-phenyl-2-propylidene)benzenamine
EINECS	Contact for details

Quality Control

Our production of 2-[(4-Fluorophenyl)Methylideneamino]-3-Phenyl-Propan-1-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities that follow cGMP principles where applicable. Comprehensive analytical control, including HPLC, GC, and NMR, is employed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.