Description

L-Alanine, N-(Hydroxymethyl)- (9Ci) is a chemically modified derivative of the essential amino acid L-alanine, characterized by the introduction of a hydroxymethyl group onto the nitrogen atom. This structural modification imparts unique reactivity and functionality, making it a valuable building block in organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in peptide mimetics and prodrug design.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators that require specific chiral centers for biological activity.
• Bioconjugation & Linker Chemistry: The hydroxymethyl group serves as a functional handle for attaching fluorescent probes, affinity tags, or other molecules in bioconjugation applications.
• Peptide Modification: Employed to introduce hydroxymethylated amino acid residues into synthetic peptides, altering their stability, solubility, or receptor binding properties.
• Cross-linking Agent: Acts as a monomer or cross-linker in the synthesis of specialty polymers, resins, and hydrogels with tailored properties.
• Chemical Research: Serves as a standard or reagent in methodological development for asymmetric synthesis and N-functionalization reactions.

Basic Information

Product Name	L-Alanine, N-(Hydroxymethyl)- (9Ci)
CAS No.	19026-60-9
Molecular Formula	C₄H₉NO₃
Molecular Weight	119.12 g/mol
Synonyms	N-(Hydroxymethyl)-L-alanine; (S)-2-Amino-N-(hydroxymethyl)propanamide; L-Alanine, N-(hydroxymethyl)-; Hydroxymethyl-L-alanine; Alanine, N-(hydroxymethyl)-, L-; 19026-60-9; N-Methylol-L-alanine
EINECS	Contact for details

Quality Control

Our L-Alanine, N-(Hydroxymethyl)- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment supports applications requiring reliable and traceable raw materials for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.