Description

Boc-D-Phenylalanine is a high-purity, enantiomerically pure amino acid derivative where the amine group is protected by a tert-butoxycarbonyl (Boc) group. This chiral building block is essential for the synthesis of complex peptides and peptidomimetics, offering critical control over stereochemistry and reaction pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of peptide-based drugs, protease inhibitors, and other bioactive molecules.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid building block for the controlled, sequential assembly of custom peptides.
• Asymmetric Synthesis: Serves as a starting material or chiral auxiliary in the preparation of enantiomerically pure compounds for medicinal chemistry.
• Biochemical Research: Employed in studies of enzyme-substrate interactions, receptor binding, and metabolic pathways.
• Process Chemistry & Scale-Up: Critical for developing robust and scalable manufacturing routes for pharmaceutical candidates.

Basic Information

Product Name	Boc-D-Phenylalanine
CAS No.	18942-49-9
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropanoic acid; D-Boc-Phenylalanine; N-Boc-D-Phenylalanine; N-(tert-Butoxycarbonyl)-D-phenylalanine; Boc-D-Phe-OH; (R)-2-(Boc-amino)-3-phenylpropionic acid; tert-Butyloxycarbonyl-D-phenylalanine; BOC-D-PHE
EINECS	242-714-4

Quality Control

Our Boc-D-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.