Description

Boc-Cys(4-Meobzl)-Oh is a protected cysteine derivative, specifically N-α-(tert-Butoxycarbonyl)-S-(4-methoxybenzyl)-L-cysteine. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), where it provides orthogonal protection for the thiol group of cysteine, preventing unwanted side reactions during peptide chain assembly. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, reliable intermediates for synthesizing peptides containing cysteine residues.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the controlled incorporation of cysteine into peptide sequences.
• Pharmaceutical Intermediates: Used in the research and development of therapeutic peptides, including hormones, enzyme inhibitors, and antimicrobial peptides.
• Bioconjugation Chemistry: Serves as a precursor for introducing thiol-reactive handles or for forming disulfide bridges in engineered proteins and antibody-drug conjugates (ADCs).
• Chemical Biology Research: Employed in the synthesis of peptide probes, substrates, and inhibitors for studying protein function and enzyme mechanisms.
• Custom Peptide Services: A fundamental reagent for CROs and CDMOs offering bespoke peptide manufacturing.

Basic Information

Product Name	Boc-Cys(4-Meobzl)-Oh
CAS No.	18942-46-6
Molecular Formula	C₁₆H₂₃NO₅S
Molecular Weight	341.42 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-S-(4-methoxybenzyl)-L-cysteine; Boc-Cys(Mob)-OH; Boc-L-cysteine(S-4-methoxybenzyl); Boc-Cys(4-MeOBzl)-OH; (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[(4-methoxyphenyl)methylsulfanyl]propanoic acid; Boc-Cys(Mob)-OH; tert-Butoxycarbonyl-S-(4-methoxybenzyl)-L-cysteine; Boc-S-(4-methoxybenzyl)-L-cysteine
EINECS	Contact for details

Quality Control

Our Boc-Cys(4-Meobzl)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation	-20° to -24° (c=1 in DMF)
Specific Impurities (HPLC)	Individual unknown ≤0.5%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.