Description

2-Iodo-Terephthalonitrile is a high-value halogenated aromatic nitrile building block, essential for advanced organic synthesis. Its unique structure, featuring both an iodine substituent and two cyano groups on a benzene ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and the synthesis of functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functionalities.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Functional Material Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its rigid, functionalizable core.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Item	Detail
Product Name	2-Iodo-Terephthalonitrile
CAS No.	18870-14-9
Molecular Formula	C8H3IN2
Molecular Weight	254.03 g/mol
Synonyms	2-Iodoterephthalonitrile; 1,4-Dicyano-2-iodobenzene; 2-Iodo-1,4-dicyanobenzene; 2-Iodobenzene-1,4-dicarbonitrile; Terephthalonitrile, 2-iodo-; 2-Iodo-p-phthalodinitrile
EINECS	Contact for details

Quality Control

Our 2-Iodo-Terephthalonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.