Description

7-Chlorohept-1-yne is a versatile aliphatic building block featuring both a terminal alkyne and a reactive chloroalkyl chain. This bifunctional nature makes it a valuable intermediate for constructing complex molecular architectures through selective coupling and substitution reactions. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, polymer science, and ligand synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and novel drug candidates via Sonogashira, click chemistry, and other cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific alkyne-functionalized side chains.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and functionalized surfaces with tailored properties.
• Ligand & Catalyst Development: Employed in the synthesis of novel phosphine, N-heterocyclic carbene (NHC), and other chelating ligands for catalytic systems.
• Organic Synthesis & Research: A fundamental reagent for constructing carbon-carbon bonds and introducing functionalized heptyl chains into complex organic molecules in R&D laboratories.
• Chemical Probes & Bio-conjugation: Useful for creating chemical probes, fluorescent tags, and bioconjugation linkers due to its reactive alkyne handle.

Basic Information

Product Name	7-Chlorohept-1-yne
CAS No.	18804-36-9
Molecular Formula	C7H11Cl
Molecular Weight	130.62 g/mol
Synonyms	1-Chloro-6-heptyne; 6-Heptyn-1-yl chloride; Hept-6-yn-1-yl chloride; 7-Chloro-1-heptyne; (6-Chlorohexyl)acetylene; 1-Heptyne, 7-chloro-; 18804-36-9 (CAS)
EINECS	Contact for details

Quality Control

Our 7-Chlorohept-1-yne is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flame. Due to its highly volatile nature, keep container tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.