Description

Boc-D-Glu(Obzl)-Osu is a protected amino acid derivative widely used as a key building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptides with precise stereochemistry. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial intermediate for the controlled, sequential addition of D-glutamic acid residues in peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for the synthesis of specific peptide fragments and conjugates.
• Pharmaceutical Research & Development: Serves as a building block for creating peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Facilitates the attachment of peptides to other molecules, such as proteins, dyes, or solid surfaces, for diagnostic and labeling applications.
• Chemical Biology Probes: Used to synthesize modified peptides for studying protein-protein interactions and enzyme mechanisms.
• Custom Peptide Service Providers: A standard reagent for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	Boc-D-Glu(Obzl)-Osu
CAS No.	18800-76-5
Molecular Formula	C19H24N2O8
Molecular Weight	408.41 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-glutamic acid 5-benzyl ester N-succinimidyl ester; Boc-D-Glu(OBzl)-OSu; Boc-D-Glu(OBzl)-ONSu; N-Boc-D-glutamic acid 5-benzyl ester N-hydroxysuccinimide ester; Nα-Boc-D-glutamic acid γ-benzyl ester N-succinimidyl ester; (2R)-5-(Benzyloxy)-2-[[(2-methylpropan-2-yl)oxycarbonyl]amino]-5-oxopentanoic acid 2,5-dioxopyrrolidin-1-yl ester; Succinimidyl N-Boc-D-glutamate 5-benzyl ester
EINECS	Contact for details

Quality Control

Our Boc-D-Glu(Obzl)-Osu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, chiral purity, and residual solvent levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or CoA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.