Description

1-Acetyl-1H-Benzotriazole is a versatile and highly reactive benzotriazole derivative, primarily utilized as a key intermediate and reagent in advanced organic synthesis. Its core value lies in its ability to function as an efficient acylating agent and a protective group precursor, enabling the synthesis of complex molecules with high selectivity. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing benzotriazole or amide motifs.
• Peptide Synthesis Reagent: Used as an acylating agent in peptide coupling reactions to form amide bonds under mild conditions.
• Agrochemical Synthesis: Serves as a precursor in the manufacturing of herbicides, fungicides, and other crop protection agents.
• Polymer Chemistry: Employed in the production of specialty polymers and as a modifier to impart specific thermal or chemical resistance properties.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the acetyl group or for the protection of amines and other functional groups.
• Material Science Research: Utilized in the development of advanced materials, including corrosion inhibitors and photoactive compounds.

Basic Information

Product Name	1-Acetyl-1H-Benzotriazole
CAS No.	18773-93-8
Molecular Formula	C8H7N3O
Molecular Weight	161.16 g/mol
Synonyms	1-Acetylbenzotriazole; 1H-Benzotriazole, 1-acetyl-; N-Acetylbenzotriazole; Acetylbenzotriazole; BTA-Ac; 1-Acetyl-1,2,3-benzotriazole; 1-Acetylbenzotriazole; N-Acetyl-1H-benzotriazole
EINECS	Contact for details

Quality Control

Our 1-Acetyl-1H-Benzotriazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	135 - 140 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.