Description

α-Apo-Oxytetracycline is a key chemical intermediate and derivative of the oxytetracycline class of antibiotics. This compound is essential for research and development in pharmaceutical synthesis, particularly for creating novel tetracycline-based therapeutics. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and life science sectors for process development and analytical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of oxytetracycline and related antibiotic compounds.
• Research & Development: Used in academic and industrial laboratories for studying tetracycline metabolism, degradation pathways, and structure-activity relationships (SAR).
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.
• Veterinary Medicine Research: Investigated for potential applications in developing treatments for bacterial infections in animals.
• Agrochemical Development: Explored for use in creating novel crop protection agents with antibacterial properties.
• Biochemical Studies: Utilized in microbiological and enzymatic studies to understand antibiotic mechanisms of action and resistance.

Basic Information

Product Name	α-Apo-Oxytetracycline
CAS No.	18695-01-7
Molecular Formula	C22H22N2O8
Molecular Weight	442.42 g/mol
Synonyms	4-Epioxytetracycline; 4-Epi-OTC; 5-Hydroxy-α-6-deoxyoxytetracycline; α-Apooxytetracycline; Apo-oxytetracycline; 4-Epioxytetracycline impurity; (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
EINECS	Contact for details

Quality Control

Our α-Apo-Oxytetracycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.