Description

N2-[(1-[1,1'-Biphenyl]-4-Yl-1-Methylethoxy)Carbonyl]-L-Asparagine is a specialized, high-purity chemical building block designed for advanced research and pharmaceutical development. This compound is valued for its role as a protected amino acid derivative, offering precise control in complex peptide synthesis and medicinal chemistry applications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected asparagine derivative to prevent unwanted side reactions.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Bioconjugation: Employed in the design and synthesis of peptide-protein conjugates and other bioconjugates for targeted drug delivery.
• Chemical Biology Probes: Utilized in the creation of labeled peptides and probes for studying biological mechanisms and enzyme interactions.
• Fine Chemical Production: Acts as a high-value intermediate in the multi-step synthesis of complex organic molecules for various industrial applications.

Basic Information

Product Name	N2-[(1-[1,1'-Biphenyl]-4-Yl-1-Methylethoxy)Carbonyl]-L-Asparagine
CAS No.	18635-06-8
Molecular Formula	C22H24N2O5
Molecular Weight	396.44 g/mol
Synonyms	Boc-Asn(Biphenyl)-OH; N-Boc-L-Asparagine biphenylmethyl ester; N-(tert-Butoxycarbonyl)-L-asparagine 4-biphenylylmethyl ester; L-Asparagine, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(phenylmethyl)phenyl ester; 18635-06-8; N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-asparagine 4-(phenylmethyl)phenyl ester; N-Boc-Asparagine Biphenylmethyl Ester
EINECS	Contact for details

Quality Control

Our N2-[(1-[1,1'-Biphenyl]-4-Yl-1-Methylethoxy)Carbonyl]-L-Asparagine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for GMP or regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Optical Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.