Description

N(Alpha)-Bpoc-N(Epsilon)-Boc-L-Lysine is a specialized, orthogonally protected derivative of the essential amino acid L-Lysine, designed for advanced peptide synthesis. This compound matters because it provides critical selectivity in protecting group removal, enabling the precise, sequential construction of complex peptides and peptide mimetics. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, peptidomimetics, and bioconjugates, where high-fidelity synthesis is paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for the controlled incorporation of lysine residues with orthogonal side-chain protection.
• Solution-Phase Peptide Synthesis: For the synthesis of complex peptide sequences requiring selective deprotection strategies.
• Peptidomimetic Drug Discovery: Enabling the creation of novel drug candidates with enhanced stability and bioavailability.
• Bioconjugation and Labeling: Facilitating the site-specific attachment of probes, tags, or payloads to peptides and proteins via the ε-amino group.
• Combinatorial Chemistry Libraries: Serving as a versatile intermediate for generating diverse libraries of lysine-containing compounds for screening.
• Academic and Industrial Research: A fundamental reagent for studies in peptide chemistry, chemical biology, and medicinal chemistry.

Basic Information

Product Name	N(Alpha)-Bpoc-N(Epsilon)-Boc-L-Lysine
CAS No.	18635-01-3
Molecular Formula	C₂₂H₃₂N₂O₆
Molecular Weight	420.50 g/mol
Synonyms	Nα-(2-(Biphenyl-4-yl)prop-2-yloxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine; Nα-Bpoc-Nε-Boc-L-lysine; Bpoc-Lys(Boc)-OH; (S)-2-((((2-(Biphenyl-4-yl)propan-2-yl)oxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid; Boc-Lys(Bpoc)-OH; Fmoc-Lys(Boc)-OH alternative; Orthogonally protected L-Lysine; Bpoc protected lysine derivative
EINECS	Contact for details

Quality Control

Our N(Alpha)-Bpoc-N(Epsilon)-Boc-L-Lysine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.