Description

1-Benzhydrylazetidin-3-Ol is a high-purity, synthetically valuable azetidine derivative, serving as a critical chiral building block in advanced pharmaceutical synthesis. Its unique bridged structure and functional groups make it indispensable for constructing complex molecular architectures with high stereochemical control. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where its azetidine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and exploring new chemical spaces.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and other azetidine-containing compounds.

Basic Information

Product Name	1-Benzhydrylazetidin-3-Ol
CAS No.	18621-17-5
Molecular Formula	C16H17NO
Molecular Weight	239.31 g/mol
Synonyms	3-Hydroxy-1-(diphenylmethyl)azetidine; 1-(Diphenylmethyl)-3-hydroxyazetidine; 1-Benzhydryl-3-hydroxyazetidine; Azetidin-3-ol, 1-(diphenylmethyl)-; 1-(Diphenylmethyl)azetidin-3-ol; 3-Azetidinol, 1-(diphenylmethyl)-
EINECS	Contact for details

Quality Control

Our 1-Benzhydrylazetidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.