Description

(S)-(-)-1,1'-Bi-2-Naphthol CAS NO 18531-99-2 is a high-purity, enantiomerically pure chiral compound widely recognized as a versatile ligand and catalyst in asymmetric synthesis. Its significance lies in its ability to induce high enantioselectivity in a broad range of organic transformations, which is critical for producing single-enantiomer pharmaceuticals and fine chemicals. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on chiral technology and green chemistry.

Application

• As a chiral ligand in asymmetric catalysis, including hydrogenation, alkylation, and Diels-Alder reactions.
• As a resolving agent for the separation of racemic mixtures of alcohols, amines, and other chiral compounds.
• In the synthesis of enantiomerically pure pharmaceuticals and agrochemical intermediates.
• As a key component in the preparation of chiral stationary phases for analytical and preparative chromatography.
• For fundamental academic and industrial research in organometallic chemistry and stereochemistry.
• In the development of novel polymeric materials with chiral functionalities.

Basic Information

Product Name	(S)-(-)-1,1'-Bi-2-Naphthol
CAS No.	18531-99-2
Molecular Formula	C₂₀H₁₄O₂
Molecular Weight	286.32 g/mol
Synonyms	(S)-BINOL; (S)-1,1'-Bi-2-naphthol; (S)-(-)-1,1'-Binaphthyl-2,2'-diol; (S)-2,2'-Dihydroxy-1,1'-binaphthyl; (S)-(-)-Binaphthol; (S)-BINOL ligand; (S)-1,1'-Binaphthalene-2,2'-diol; (S)-(-)-2,2'-Dihydroxy-1,1'-binaphthyl
EINECS	242-418-7

Quality Control

Our (S)-(-)-1,1'-Bi-2-Naphthol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (HPLC), chemical purity (HPLC), and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Chiral Purity (HPLC)	≥ 99.5% ee
Melting Point	205 - 210 °C
Specific Rotation [α]²⁰D	-30.0° to -35.0° (c=1, THF)
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.