Description

(R)-(+)-1,1'-Bi-2-Naphthol CAS NO 18531-94-7 is a high-purity, enantiomerically pure chiral compound belonging to the class of binaphthyl derivatives. This compound is a crucial chiral auxiliary and ligand in asymmetric synthesis, enabling the production of single-enantiomer pharmaceuticals and fine chemicals with high stereoselectivity. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and advanced materials sectors where precise chirality control is paramount.

Application

• As a chiral ligand in asymmetric catalysis (e.g., hydrogenation, oxidation, C-C bond formation).
• As a resolving agent for the separation of racemic mixtures.
• As a key building block for synthesizing chiral phosphoric acids and other complex ligands.
• In the research and development of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• For the synthesis of chiral polymers and advanced functional materials.
• In academic and industrial research for methodological development in organic chemistry.

Basic Information

Product Name	(R)-(+)-1,1'-Bi-2-Naphthol
CAS No.	18531-94-7
Molecular Formula	C₂₀H₁₄O₂
Molecular Weight	286.32 g/mol
Synonyms	(R)-(+)-1,1'-Bi-2-naphthol; (R)-BINOL; (R)-(+)-BINOL; (R)-1,1'-Bi-2-naphthol; (R)-(+)-1,1'-Binaphthalene-2,2'-diol; (R)-2,2'-Dihydroxy-1,1'-binaphthyl; (R)-Binaphthol; (R)-1,1'-Binaphthyl-2,2'-diol
EINECS	Contact for details

Quality Control

Our (R)-(+)-1,1'-Bi-2-Naphthol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for asymmetric synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Melting Point	205 - 210 °C
Specific Rotation	+34.0° to +36.0° (c=1, THF)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.