Description

1-Bromo-2-Octyne is a versatile alkyne building block with a terminal bromine atom, offering a reactive handle for advanced organic synthesis. This compound is valued for its role in cross-coupling reactions and as a key intermediate in the development of complex molecular architectures. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific carbon chains or functional groups.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of specialized pesticides, herbicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or precursor in the development of polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An effective substrate for Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Organic Synthesis Reagent: Employed in laboratories for the introduction of an octyne moiety into target molecules for structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Utilized in the creation of tagged molecules and probes for biochemical and cellular research applications.

Basic Information

Product Name	1-Bromo-2-Octyne
CAS No.	18495-27-7
Molecular Formula	C8H13Br
Molecular Weight	189.09 g/mol
Synonyms	2-Octyn-1-yl Bromide; 1-Bromo-2-octyne; Bromooctyne; 1-Bromo-oct-2-yne; Oct-2-yn-1-yl bromide; 2-Octyne, 1-bromo-; Bromomethylpentylacetylene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Octyne is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.