Description

Brompheniramine n-Oxide is a key pharmaceutical intermediate and metabolite of the antihistamine brompheniramine. This compound is essential for research and development in pharmacology and analytical chemistry, particularly in metabolic pathway studies and reference standard preparation. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) and diagnostic reagents.

Application

• Pharmaceutical Intermediate: Critical for the synthesis and development of antihistamine drugs and related analogs.
• Metabolite Reference Standard: Used as a certified reference material (CRM) in bioanalytical studies to identify and quantify metabolites in pharmacokinetic and toxicological research.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate the metabolic fate, activity, and degradation pathways of brompheniramine.
• Quality Control & Analytical Testing: Serves as a high-purity standard in HPLC, LC-MS, and other chromatographic methods for assay and impurity profiling in pharmaceutical manufacturing.
• Academic Research: Used in university and institutional labs for studies in medicinal chemistry, pharmacology, and drug metabolism.

Basic Information

Item	Details
Product Name	Brompheniramine n-Oxide
CAS No.	18453-29-7
Molecular Formula	C16H19BrN2O
Molecular Weight	335.24 g/mol
Synonyms	Brompheniramine N-Oxide; Brompheniramine Oxide; 3-(4-Bromophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine N-Oxide; Brompheniramine Metabolite; Parabromdylamine N-Oxide; Dimegan N-Oxide; Ilvin N-Oxide
EINECS	Contact for details

Quality Control

Our Brompheniramine n-Oxide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.