Description

Coenzyme A Trilithium Salt is a high-purity, biologically active form of the essential cofactor Coenzyme A, stabilized as its trilithium salt. This compound is critical for facilitating acyl group transfer reactions in numerous metabolic pathways, including the citric acid cycle and fatty acid synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors for enzyme studies, biochemical assays, and the production of high-value fine chemicals.

Application

• Biochemical Research & Enzyme Assays: Essential substrate or cofactor in in vitro studies of acyltransferase, synthetase, and other CoA-dependent enzymes.
• Pharmaceutical Intermediate: Used in the synthesis of specialized pharmaceutical compounds and active pharmaceutical ingredients (APIs) that require CoA-mediated transformations.
• Diagnostic Reagent Manufacturing: A key component in the formulation of clinical diagnostic kits for measuring specific enzyme activities (e.g., for liver function).
• Metabolomics & Cell Culture Studies: Employed to supplement cell culture media or in metabolic flux analysis to study central carbon metabolism.
• Biocatalysis: Serves as a cofactor in enzymatic synthesis processes for the production of chiral compounds and other fine chemicals.
• Reference Standard: Used as a high-purity calibrant or standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	Coenzyme A Trilithium Salt
CAS No.	18439-24-2
Molecular Formula	C21H33Li3N7O16P3S
Molecular Weight	785.29 g/mol
Synonyms	CoA Trilithium Salt; CoASH-Li3; Coenzyme A (Lithium Salt); Lithium Coenzyme A; 3'-Phosphoadenosine 5'-diphospho-pantetheine Lithium Salt; S-[2-(3-Carbamoyl-3,3-dimethylpropylcarbamoyl)ethyl]-3-oxo-L-cysteine 1-(adenosine-3',5'-diphosphate) Trilithium Salt; CoA Li Salt; Coenzyme A (free acid) trilithium salt
EINECS	242-324-4

Quality Control

Our Coenzyme A Trilithium Salt is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for research and commercial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	5.0 - 7.0
Biological Activity	Conforms (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.