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(4-Fluorophenyl)Diphenylphosphane CAS NO 18437-72-4


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CAS No.:18437-72-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(4-Fluorophenyl)Diphenylphosphane is a versatile organophosphorus compound featuring a fluorinated aromatic substituent. This structure makes it a valuable ligand and building block in advanced synthetic chemistry, particularly in catalytic systems and materials science. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds and enhance reaction efficiencies.

Application

  • Pharmaceutical Intermediates: Serves as a key precursor and ligand in the synthesis of active pharmaceutical ingredients (APIs), especially for cross-coupling reactions like Suzuki-Miyaura and Heck reactions.
  • Catalyst Ligand for Homogeneous Catalysis: Used as a phosphine ligand to modulate the activity and selectivity of transition metal catalysts (e.g., Pd, Pt, Rh) in fine chemical production.
  • Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides due to its unique electronic properties imparted by the fluorine atom.
  • Material Science & OLED Development: Acts as a building block for creating phosphorescent materials and electron-transport layers in organic light-emitting diodes (OLEDs).
  • Academic & Industrial Research: A critical reagent for methodological development in organic synthesis and organometallic chemistry.
  • Liquid Crystal and Polymer Additives: Can be utilized in the synthesis of specialty monomers and additives to modify polymer properties.

Basic Information

Product Name (4-Fluorophenyl)Diphenylphosphane
CAS No. 18437-72-4
Molecular Formula C18H14FP
Molecular Weight 280.28 g/mol
Synonyms (4-Fluorophenyl)diphenylphosphine; 4-Fluorophenyldiphenylphosphine; Diphenyl(4-fluorophenyl)phosphine; (p-Fluorophenyl)diphenylphosphine; P-(4-Fluorophenyl)diphenylphosphine; 1-Fluoro-4-(diphenylphosphino)benzene; (4-Fluorophenyl)diphenylphosphane; 4-Fluorotriphenylphosphine (common misnomer, structurally distinct)
EINECS Contact for details

Quality Control

Our (4-Fluorophenyl)Diphenylphosphane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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