Description

tert-Butyl 3-Nitrophenylcarbamate is a protected aniline derivative and a versatile chemical intermediate of significant importance in synthetic organic chemistry. Its core value lies in providing a masked amine functionality, enabling selective chemical transformations that are critical for constructing complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing substituted aniline moieties.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides where the nitro and protected amine groups serve as handles for further functionalization.
• Peptide Chemistry & Protecting Groups: The tert-butyloxycarbonyl (Boc) group serves as a crucial amine-protecting group in solid-phase peptide synthesis (SPPS) and other multi-step organic syntheses.
• Dye & Pigment Manufacturing: Intermediate for the preparation of azo dyes and other complex colorants, leveraging the reactivity of the nitroarene structure.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	tert-Butyl 3-Nitrophenylcarbamate
CAS No.	18437-64-4
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	3-Nitro-N-(tert-butoxycarbonyl)aniline; tert-Butyl (3-nitrophenyl)carbamate; N-Boc-3-nitroaniline; Carbamic acid, N-(3-nitrophenyl)-, 1,1-dimethylethyl ester; BOC-3-Nitroaniline; 1,1-Dimethylethyl N-(3-nitrophenyl)carbamate; tert-Butyl 3-nitrobenzenecarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Nitrophenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics is provided with every shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.