Description

Ethyl Hexafluoroglutaryl Chloride is a highly reactive fluorinated acid chloride derivative, serving as a critical building block for introducing the hexafluoroglutaryl moiety into target molecules. Its primary value lies in enabling the synthesis of complex fluorinated compounds, which are prized for their enhanced stability, lipophilicity, and unique electronic properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the production of fluorinated active pharmaceutical ingredients (APIs), potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, where the fluorine atoms can improve efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty fluoropolymers with high thermal and chemical resistance.
• Liquid Crystal & OLED Materials: A valuable intermediate for synthesizing fluorinated components used in electronic displays and organic light-emitting diodes.
• Peptide & Protein Modification: Employed to introduce fluorinated acyl groups into biomolecules for research and diagnostic applications.
• Complex Ligand Synthesis: Facilitates the creation of fluorinated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Ethyl Hexafluoroglutaryl Chloride
CAS No.	18381-53-8
Molecular Formula	C7H5ClF6O2
Molecular Weight	270.56 g/mol
Synonyms	Hexafluoroglutaryl Chloride Ethyl Ester; Ethyl 5-Chloro-4,4,5,5,6,6,6-heptafluoro-3-oxohexanoate; 5-Chloro-4,4,5,5,6,6,6-heptafluoro-3-oxohexanoic Acid Ethyl Ester; Ethyl 5-Chloro-4,4,5,5,6,6,6-heptafluoro-3-oxohexanoate; Heptafluoroglutaryl Chloride Ethyl Derivative; EFGC; Fluorinated Glutaryl Chloride Ester
EINECS	Contact for details

Quality Control

Our Ethyl Hexafluoroglutaryl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets stringent specifications for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at recommended temperatures between 2°C and 8°C. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) and away from strong acids, bases, and moisture. Handle and open containers only in a controlled, dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acid Chloride Content	≥ 97.0% (by titration)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.