Description

Salicylamide Glucuronide is a crucial metabolite formed from the conjugation of salicylamide with glucuronic acid. This compound is of significant importance in pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and toxicology. It serves as a key analytical reference standard for laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the quantification and qualification of salicylamide and its metabolites in biological matrices.
• Drug Metabolism & Pharmacokinetics (DMPK) Studies: Essential for investigating the metabolic pathways, bioavailability, and clearance rates of salicylamide-based therapeutics.
• Toxicological Research: Used to study the biotransformation and potential toxic effects of salicylamide, aiding in safety assessments.
• Analytical Method Development: Serves as a critical standard for developing and validating high-performance liquid chromatography (HPLC), LC-MS/MS, and other analytical methods.
• Enzyme Activity Assays: Employed in studies to assess the activity of UDP-glucuronosyltransferase (UGT) enzymes responsible for glucuronidation.
• Clinical Research: Supports studies on individual variation in drug metabolism and personalized medicine approaches.

Basic Information

Product Name	Salicylamide Glucuronide
CAS No.	18338-81-3
Molecular Formula	C13H15NO8
Molecular Weight	313.26 g/mol
Synonyms	Salicylamide O-β-D-Glucuronide; 2-Hydroxybenzamide Glucuronide; Salicylamide β-D-Glucopyranosiduronic Acid; Salicylamide 1-O-β-D-Glucuronide; Salicylamide Glucuronide Sodium Salt (common salt form); O-Glucuronosyl-salicylamide; Benzamide, 2-hydroxy-, 1-(β-D-glucopyranuronosyl)
EINECS	Contact for details

Quality Control

Our Salicylamide Glucuronide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and analytical applications. Each lot is thoroughly characterized using advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.