Description

[1S,5R,(+)]-2-Isopropylidene-N,N,5-Trimethylcyclopentanemethanamine is a high-purity, chiral amine derivative with a defined stereochemistry, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical sector where stereochemical purity is paramount. This compound is essential for research chemists and process development scientists in pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where specific stereoisomers often exhibit enhanced biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in asymmetric catalysis (e.g., hydrogenation, alkylation).
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	[1S,5R,(+)]-2-Isopropylidene-N,N,5-Trimethylcyclopentanemethanamine
CAS No.	17943-85-0
Molecular Formula	C13H25N
Molecular Weight	195.35 g/mol
Synonyms	(1S,5R)-(+)-2-Isopropylidene-5-methyl-1-(N,N-dimethylaminomethyl)cyclopentane; (1S,5R)-(+)-N,N,5-Trimethyl-2-(1-methylethylidene)cyclopentanemethanamine; (+)-cis-2-Isopropylidene-N,N,5-trimethylcyclopentanemethanamine; (1S,5R)-2-Isopropylidene-N,N,5-trimethylcyclopentanemethanamine; Chiral Isopropylidene Trimethylcyclopentanemethanamine; (1S,5R)-Isomer of 17943-85-0
EINECS	Contact for details

Quality Control

Our [1S,5R,(+)]-2-Isopropylidene-N,N,5-Trimethylcyclopentanemethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC, GC), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, assay, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.