Description

Ac-D-Val-Oh is a high-purity, protected D-valine derivative, a crucial chiral building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for the production of complex peptides, peptidomimetics, and active pharmaceutical ingredients (APIs), where stereochemical integrity is paramount. This product is essential for research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of peptide-based drugs and novel therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the D-valine residue into peptide chains, influencing structure and bioactivity.
• Protease Inhibitor Development: Serves as a building block for creating inhibitors that target specific enzymes.
• Bioconjugation & Labeling: The acetyl-protected amino acid can be utilized in the preparation of labeled peptides or protein conjugates for diagnostic and research applications.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the structure-activity relationships (SAR) of bioactive peptides.
• Fine Chemical Synthesis: Acts as a precursor for more complex, non-natural amino acids and specialty organic compounds.

Basic Information

Product Name	Ac-D-Val-Oh
CAS No.	17916-88-0
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	N-Acetyl-D-valine; Ac-D-Val-OH; (R)-2-Acetamido-3-methylbutanoic acid; D-N-Acetylvaline; N-Acetyl-D-valine; N-Acetyl-(R)-valine; Ac-D-Val; N-Acetyl-D-2-amino-3-methylbutyric acid
EINECS	Contact for details

Quality Control

Our Ac-D-Val-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.