Description

16-Oxoestradiol 3-Sulfate is a sulfated metabolite of the endogenous estrogen, 16-oxoestradiol. This compound is of significant value as a high-purity reference standard and biochemical intermediate for research and development. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in steroid metabolism studies, hormone-related disease research, and analytical method development.

Application

• Biochemical Research Standard: Serves as a critical reference material for the quantification and validation of estrogen metabolites in biological samples.
• Pharmaceutical R&D: Used as an intermediate or analytical standard in the development of novel therapeutics targeting estrogen pathways.
• Clinical Diagnostics: Employed in the calibration of assays (e.g., LC-MS/MS) for measuring steroid hormone profiles in clinical laboratories.
• Metabolomics Studies: A key analyte in research focused on understanding steroid biosynthesis, metabolism, and their roles in health and disease.
• Enzyme Activity Assays: Used as a substrate to study the activity of sulfotransferase and sulfatase enzymes in vitro.

Basic Information

Product Name	16-Oxoestradiol 3-Sulfate
CAS No.	17916-85-7
Molecular Formula	C18H22O6S
Molecular Weight	366.43 g/mol
Synonyms	16-Oxoestradiol 3-Sulfate; 16-Oxoestra-1,3,5(10)-triene-3,17β-diol 3-Sulfate; Estra-1,3,5(10)-triene-3,16,17-triol, 3-sulfate; 16-Ketoestradiol 3-Sulfate; 16-Oxo-E2 3-Sulfate
EINECS	Contact for details

Quality Control

Our 16-Oxoestradiol 3-Sulfate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the stringent requirements for research-grade materials. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.