Description

β-Msh, Human is a synthetic peptide hormone, specifically the human β-melanocyte-stimulating hormone, with the CAS registry number 17908-57-5. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in melanogenesis and appetite regulation. It is a critical reagent for researchers and developers in the fields of endocrinology, dermatology, and metabolic disorder studies. The product is supplied as a high-purity material suitable for demanding laboratory and pre-clinical applications.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating melanocortin receptor (MCR) signaling pathways, particularly MC1R and MC4R.
• Pharmacological Studies: Essential for in vitro and in vivo assays to evaluate the efficacy and mechanism of action of new therapeutics targeting obesity, skin pigmentation disorders, and inflammation.
• Diagnostic Development: Serves as a key component in the development of immunoassays (ELISA, RIA) for the quantitative detection of related peptides and antibodies.
• Peptide Chemistry: Acts as a building block or a comparative model in peptide synthesis and structure-activity relationship (SAR) studies.
• Cell Culture & Signaling: Applied in cell-based experiments to stimulate specific receptor-mediated responses and study downstream cellular events.

Basic Information

Product Name	β-Msh, Human
CAS No.	17908-57-5
Molecular Formula	C₉₉H₁₄₀N₂₈O₃₁S₂
Molecular Weight	2295.5 g/mol
Synonyms	Human β-MSH; β-Melanocyte Stimulating Hormone (Human); β-Melanotropin (Human); β-MSH (1-22), human; H-Asp-Ser-Gly-Pro-Tyr-Lys-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp-OH; Melanocyte-Stimulating Hormone beta; β-Lipotropin (41-58), human; Intermedin (41-58)
EINECS	Contact for details

Quality Control

Our β-Msh, Human is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including reversed-phase HPLC for purity assessment, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.