Description

Methyl 2-Fluoro-2-Phenylacetate is a versatile fluorinated ester building block of significant interest in advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom adjacent to a carbonyl group, which can dramatically influence the reactivity, metabolic stability, and physical properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of fluorinated analogs of bioactive molecules, potentially enhancing their potency, selectivity, and pharmacokinetic profiles.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atom can improve lipophilicity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic esters used in electronic display technologies and organic semiconductors.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic substitution and other reactions at a benzylic carbon bearing both fluorine and ester functionalities.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex fluorinated fragrances, flavors, and other specialty chemicals.

Basic Information

Product Name	Methyl 2-Fluoro-2-Phenylacetate
CAS No.	17841-30-4
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	2-Fluoro-2-phenylacetic acid methyl ester; Methyl α-fluorophenylacetate; α-Fluorophenylacetic acid methyl ester; Methyl (2-fluoro-2-phenyl)acetate; Methyl DL-2-fluoro-2-phenylacetate; Methyl 2-fluoro-2-phenylacetate; Phenylfluoromethyl acetate; Methyl (fluorophenyl)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-2-Phenylacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability, although the product is typically stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.