Description

4-Hydroxymercuribenzenesulfonate is a specialized organomercury compound used as a critical reagent in biochemical research and analytical chemistry. Its primary value lies in its ability to act as a selective sulfhydryl group modifier, enabling the study of protein structure and enzyme activity. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise and reliable tools for molecular interaction studies and assay development.

Application

• Biochemical Research: As a specific reagent for the modification of cysteine residues in proteins and enzymes to study structure-function relationships.
• Enzyme Inhibition Studies: Used to investigate the role of thiol groups in enzymatic catalysis and mechanism.
• Analytical Chemistry: Employed in the development of sensitive assays and as a reference standard in chromatographic analysis.
• Pharmaceutical Development: Serves as a tool compound in drug discovery for probing binding sites and validating biological targets.
• Diagnostic Reagent Manufacturing: A key component in the formulation of specific test kits and diagnostic solutions.

Basic Information

Product Name	4-Hydroxymercuribenzenesulfonate
CAS No.	17781-34-9
Molecular Formula	C6H6HgO4S
Molecular Weight	374.75 g/mol
Synonyms	p-Hydroxymercuribenzenesulfonic Acid; (4-Sulfophenyl)mercuric Hydroxide; Hydroxy(4-sulfophenyl)mercury; Mercury, hydroxy(4-sulfophenyl)-; p-Hydroxymercuriphenylsulfonate; PHMBS; 4-Hydroxymercuriphenylsulfonic Acid; Hydroxy(4-sulfophenyl)mercury(II)
EINECS	241-750-6

Quality Control

Our 4-Hydroxymercuribenzenesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is strictly light-sensitive, easily oxidized, and hygroscopic. For long-term stability, storage under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment is strongly recommended.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
Mercury Content	52.5 - 54.5 %
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.