Description

(2,6-Difluoro-Benzyl)-Urea is a specialized fluorinated urea derivative, a key building block in advanced organic synthesis. This compound matters for its role in creating complex molecules with enhanced biological activity and physicochemical properties, driven by the strategic placement of fluorine atoms on the benzyl ring. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by fine chemical manufacturers producing high-value intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other enzyme modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the difluorobenzyl moiety can improve metabolic stability and bioavailability.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study biological pathways and protein functions.
• Material Science Applications: Can be incorporated into the synthesis of specialty polymers or ligands for catalysts, leveraging its unique electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	(2,6-Difluoro-Benzyl)-Urea
CAS No.	17751-24-5
Molecular Formula	C8H8F2N2O
Molecular Weight	186.16 g/mol
Synonyms	1-[(2,6-Difluorophenyl)methyl]urea; Urea, N-[(2,6-difluorophenyl)methyl]-; (2,6-Difluorobenzyl)urea; N-(2,6-Difluorobenzyl)urea; 2,6-Difluorobenzylurea; 17751-24-5; (2,6-Difluoro-benzyl)-urea
EINECS	Contact for details

Quality Control

Our (2,6-Difluoro-Benzyl)-Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.