Description

D-Proline, 3,4-Dihydroxy-, (3S,4R)-Rel- (9Ci) is a chiral, non-proteinogenic amino acid derivative characterized by its unique dihydroxylated proline structure. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with high stereochemical fidelity. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including protease inhibitors and other biologically active molecules.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective chemical transformations.
• Peptidomimetics Research: Incorporated into peptide analogs to study structure-activity relationships and enhance metabolic stability.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway investigations.
• Agrochemical Synthesis: An intermediate in the production of advanced, stereochemically defined pesticides and herbicides.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	D-Proline, 3,4-Dihydroxy-, (3S,4R)-Rel- (9Ci)
CAS No.	17663-43-3
Molecular Formula	C₅H₉NO₄
Molecular Weight	147.13 g/mol
Synonyms	(3S,4R)-3,4-Dihydroxy-D-proline; rel-(3S,4R)-3,4-Dihydroxy-D-proline; 3,4-Dihydroxy-D-proline; D-3,4-Dihydroxypyrrolidine-2-carboxylic Acid; (2R,3S,4R)-3,4-Dihydroxypyrrolidine-2-carboxylic Acid; 17663-43-3; (3S,4R)-3,4-Dihydroxypyrrolidine-2-carboxylic Acid (D-form)
EINECS	Contact for details

Quality Control

Every batch of our D-Proline, 3,4-Dihydroxy-, (3S,4R)-Rel- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity requirements for research and synthesis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identification is supplied with each shipment. Our quality protocols are designed to support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.