Description

Didesethylflurazepam CAS NO 17617-59-3 is a high-purity benzodiazepine derivative and a key intermediate in pharmaceutical research and development. This compound is critical for the synthesis and analytical profiling of active pharmaceutical ingredients (APIs) and their metabolites. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in drug discovery, process development, and quality control.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex benzodiazepine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical testing.
• Metabolite Studies: Serves as a key compound in pharmacokinetic and metabolic pathway research for related therapeutic agents.
• Forensic Analysis: Employed as an analytical standard in forensic toxicology laboratories for the identification and quantification of substances.
• Academic & Contract Research: Utilized in university and CRO settings for medicinal chemistry research and the development of new therapeutic entities.
• Impurity Profiling: Acts as a known impurity or degradation product standard to ensure the purity and safety of final drug products.

Basic Information

Product Name	Didesethylflurazepam
CAS No.	17617-59-3
Molecular Formula	C₁₅H₁₀ClFN₂O
Molecular Weight	288.70 g/mol
Synonyms	7-Chloro-1-(2-fluorophenyl)-1,3-dihydro-5H-1,4-benzodiazepin-2-one; 1,4-Benzodiazepin-2-one, 7-chloro-1-(2-fluorophenyl)-1,3-dihydro-; Didesethyl Flurazepam; Ro 07-9749/000; Flurazepam Impurity D (EP); Flurazepam Related Compound D (USP); Flurazepam Didesethyl
EINECS	Contact for details

Quality Control

Our Didesethylflurazepam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all test results against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.