Description

Boc-β-Ala-Onp CAS NO 17547-09-0 is a specialized, high-purity chemical building block used in advanced organic synthesis. This compound is critically important for the controlled introduction of the Boc-protected β-alanine moiety into peptide chains and other complex molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, prodrugs, and bioconjugates.

Application

• Peptide Synthesis: A key reagent for the solid-phase and solution-phase synthesis of peptides, particularly for incorporating β-alanine spacers or linkers.
• Prodrug Development: Used to create ester-based prodrugs, enhancing the bioavailability and pharmacokinetic profile of active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the covalent attachment of peptides, drugs, or labels to proteins, antibodies, or nanoparticles for targeted delivery and diagnostics.
• Chemical Biology Research: Serves as a versatile tool for modifying biomolecules to study protein function, interactions, and cellular pathways.
• Material Science: Employed in the synthesis of functionalized polymers and dendrimers with specific biological or chemical properties.
• Intermediate for Fine Chemicals: Acts as a crucial intermediate in the multi-step synthesis of complex organic compounds for pharmaceutical and agrochemical applications.

Basic Information

Item	Detail
Product Name	Boc-β-Ala-Onp
CAS No.	17547-09-0
Molecular Formula	C₁₄H₁₈N₂O₆
Molecular Weight	310.30 g/mol
Synonyms	Boc-β-Ala-ONp; tert-Butyloxycarbonyl-β-alanine p-nitrophenyl ester; N-(tert-Butoxycarbonyl)-β-alanine 4-nitrophenyl ester; p-Nitrophenyl N-Boc-β-alaninate; Boc-β-Ala-ONp ester; BOC-β-Alanine p-Nitrophenyl Ester; N-Boc-3-aminopropanoic acid 4-nitrophenyl ester; (3-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]propanoic acid 4-nitrophenyl ester)
EINECS	Contact for details

Quality Control

Our Boc-β-Ala-Onp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.