Description

3,3,3-Trifluoro-Dl-Alanine is a non-natural, fluorinated amino acid derivative of significant interest in advanced chemical synthesis. Its core value lies in the unique properties imparted by the trifluoromethyl group, which can dramatically alter the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and as a sophisticated building block in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of fluorinated peptides, peptidomimetics, and potential drug candidates targeting metabolic diseases and CNS disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Biochemical Probe Development: Serves as a valuable tool in mechanistic studies and enzyme inhibition assays due to its ability to mimic natural alanine while resisting metabolic degradation.
• Material Science: Incorporated into specialty polymers and coatings to modify surface properties, such as oil and water repellency (fluorination).
• Positron Emission Tomography (PET) Tracer Synthesis: Acts as a precursor for fluorine-18 labeled compounds used in medical imaging diagnostics.
• Asymmetric Synthesis & Catalysis: Employed as a substrate or ligand in chiral synthesis to study and induce stereoselectivity in chemical reactions.

Basic Information

Product Name	3,3,3-Trifluoro-Dl-Alanine
CAS No.	17463-43-3
Molecular Formula	C₃H₄F₃NO₂
Molecular Weight	143.06 g/mol
Synonyms	DL-3,3,3-Trifluoroalanine; 2-Amino-3,3,3-trifluoropropanoic Acid; (±)-3,3,3-Trifluoroalanine; 3,3,3-Trifluoro-DL-alanine; NSC 326330; Alanine, 3,3,3-trifluoro-; α-Amino-β,β,β-trifluoropropionic acid; Trifluoroalanine
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-Dl-Alanine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (DL Ratio)	~50:50 (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.