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Tetra-o-Acetyl-2-Amino-2-Deoxy-α-D-Glucopyranose CAS NO 17460-45-6


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CAS No.:17460-45-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Tetra-o-Acetyl-2-Amino-2-Deoxy-α-D-Glucopyranose is a key acetylated derivative of glucosamine, serving as a vital protected intermediate in organic synthesis. Its primary value lies in providing a stable, reactive scaffold for the controlled synthesis of complex carbohydrates, glycoconjugates, and nucleoside analogues. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutics, diagnostic agents, and advanced biomaterials.

Application

  • Pharmaceutical Intermediate: Critical building block for the synthesis of glycosidase inhibitors, antiviral agents, and other bioactive carbohydrate-based drugs.
  • Glycochemistry Research: Used as a protected glycosyl donor or acceptor in the synthesis of oligosaccharides and complex glycans for biological studies.
  • Nucleoside Analogue Synthesis: Serves as a precursor for modified nucleosides with potential applications in antiviral and anticancer therapies.
  • Bioconjugation & Probe Development: Facilitates the chemical modification of proteins, peptides, and other biomolecules for diagnostic and therapeutic applications.
  • Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, chiral auxiliaries, and catalysts.
  • Academic & R&D Laboratories: A standard reagent for methodological development in synthetic organic and medicinal chemistry.

Basic Information

Product Name Tetra-o-Acetyl-2-Amino-2-Deoxy-α-D-Glucopyranose
CAS No. 17460-45-6
Molecular Formula C14H21NO9
Molecular Weight 347.32 g/mol
Synonyms 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-glucopyranose; α-D-Glucopyranose, 2-(acetylamino)-1,3,4,6-tetra-O-acetyl-2-deoxy-; N-Acetylglucosamine Tetraacetate (α-form); GlcNAc Tetraacetate (α-anomer); 2-Acetamido-2-deoxy-α-D-glucopyranose Tetraacetate; 1,3,4,6-Tetra-O-acetyl-2-acetamido-2-deoxy-α-D-glucopyranose; N-Acetyl-α-D-glucosamine Tetraacetate
EINECS 241-476-9

Quality Control

Our Tetra-o-Acetyl-2-Amino-2-Deoxy-α-D-Glucopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for anomeric confirmation, and identity verification via spectroscopic methods. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere after each use to maintain stability and prevent decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Specific Rotation [α]20/D +100° to +110° (c=1 in CHCl3)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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