Description

Ac-Tyr(Ac)-OH is a protected tyrosine derivative, specifically N-acetyl-O-acetyl-L-tyrosine, widely utilized as a key synthetic intermediate in peptide chemistry and pharmaceutical research. This compound is essential for introducing modified tyrosine residues into peptide sequences while preventing unwanted side reactions during synthesis. It is primarily required by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Peptide Synthesis Intermediate: A crucial building block for the solid-phase and solution-phase synthesis of complex peptides and proteins.
• Pharmaceutical Research: Used in the development and study of peptide-based drugs, hormone analogs, and enzyme inhibitors.
• Bioconjugation & Labeling: Serves as a precursor for creating fluorescently labeled or biotinylated tyrosine derivatives for biochemical assays.
• Protecting Group Strategy: Employed in multi-step organic syntheses where selective protection and deprotection of tyrosine's functional groups are required.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in analytical laboratories.
• Biochemical Probe Development: Utilized in creating specialized probes to study tyrosine kinases and phosphorylation events in cellular signaling pathways.

Basic Information

Product Name	Ac-Tyr(Ac)-OH
CAS No.	17355-23-6
Molecular Formula	C₁₃H₁₅NO₅
Molecular Weight	265.26 g/mol
Synonyms	N-Acetyl-O-acetyl-L-tyrosine; Acetyltyrosine acetate; L-Tyrosine, N-acetyl-, acetate (ester); N-Acetyl-L-tyrosine O-acetate; Ac-Tyr(OAc)-OH; N-Acetyl-O-acetyltyrosine; (2S)-2-Acetamido-3-(4-acetoxyphenyl)propanoic acid; Acetyl tyrosine acetyl ester
EINECS	Contact for details

Quality Control

Our Ac-Tyr(Ac)-OH is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material suitable for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range available on COA
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.