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n-(Benzyloxycarbonyl)-L-Alanine Hydrazide CAS NO 17350-66-2


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CAS No.:17350-66-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(Benzyloxycarbonyl)-L-Alanine Hydrazide is a protected amino acid derivative widely used as a key synthetic intermediate in organic and peptide chemistry. Its primary value lies in providing a versatile handle for the controlled elongation and modification of peptide chains, enabling the synthesis of complex biomolecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries, particularly for developing peptide-based drugs, diagnostic agents, and advanced research materials.

Application

  • Peptide Synthesis: A crucial building block for solid-phase and solution-phase peptide synthesis, facilitating the controlled addition of alanine residues.
  • Pharmaceutical Intermediates: Serves as a key intermediate in the research and production of therapeutic peptides and peptidomimetics.
  • Bioconjugation: Used in the preparation of peptide-protein conjugates for applications in drug delivery and diagnostics.
  • Chemical Biology Research: Employed in the study of enzyme mechanisms, protein-protein interactions, and as a tool compound.
  • Fine Chemical Production: Acts as a precursor for more complex chiral molecules and specialty chemicals.
  • Protecting Group Chemistry: The benzyloxycarbonyl (Cbz) group provides orthogonal protection for amine functionalities in multi-step syntheses.

Basic Information

Product Name n-(Benzyloxycarbonyl)-L-Alanine Hydrazide
CAS No. 17350-66-2
Molecular Formula C11H15N3O3
Molecular Weight 237.26 g/mol
Synonyms CBZ-L-Alanine Hydrazide; Z-L-Ala-NHNH2; Nα-Cbz-L-alanine hydrazide; (S)-2-(((Benzyloxy)carbonyl)amino)propanehydrazide; L-Alanine, N-[(phenylmethoxy)carbonyl]-, hydrazide; Benzyloxycarbonyl-L-alanine hydrazide; Cbz-Ala-NHNH2; N-Carbobenzoxy-L-alanine hydrazide
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Quality Control

Our n-(Benzyloxycarbonyl)-L-Alanine Hydrazide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Optical Rotation [α]D20 Specific range available on COA
Melting Point Specific range available on COA
Loss on Drying ≤0.5%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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