Description

(S)-Benzyl 1-Cyanoethylcarbamate CAS NO 17343-54-3 is a high-purity, single-enantiomer chiral building block of significant importance in asymmetric synthesis. This compound is valued for its role as a protected amino acid derivative, enabling the controlled introduction of the (S)-1-aminoethyl moiety into complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical purity is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly those targeting neurological and cardiovascular diseases.
• Peptidomimetics Research: Used to incorporate non-natural amino acid residues into peptide backbones for drug discovery and biochemical studies.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological development in organic and medicinal chemistry.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for clients.

Basic Information

Product Name	(S)-Benzyl 1-Cyanoethylcarbamate
CAS No.	17343-54-3
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	(S)-1-((Benzyloxy)carbonylamino)ethyl cyanide; (S)-N-Carbobenzoxy-α-aminopropionitrile; (S)-Cbz-α-Aminopropionitrile; (S)-Benzyl N-(1-cyanoethyl)carbamate; (S)-1-Cyanoethyl carbamic acid benzyl ester; (S)-N-(Benzyloxycarbonyl)-α-aminopropionitrile; (S)-1-((Benzyloxy)carbonylamino)propanenitrile; Z-(S)-α-Aminopropionitrile
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 1-Cyanoethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.