Description

n-Benzyloxycarbonylserylleucinamide is a protected dipeptide derivative, specifically a benzyloxycarbonyl (Cbz)-protected seryl-leucine amide. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS) and other advanced organic syntheses, enabling the controlled construction of complex peptides and proteins. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of therapeutic peptides, biochemical probes, and novel bioactive compounds.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the stepwise assembly of longer peptide sequences in both solution and solid-phase synthesis.
• Pharmaceutical Research: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Tool Development: Employed in the synthesis of enzyme substrates, inhibitors, or labeled peptides for proteomics and biochemical assays.
• Academic Research: Serves as a standard or starting material in university and institutional labs studying peptide chemistry and structure-activity relationships.
• Fine Chemical Production: Acts as a specialized intermediate for custom synthesis services and the manufacture of high-value, complex organic molecules.

Basic Information

Product Name	n-Benzyloxycarbonylserylleucinamide
CAS No.	17331-87-2
Molecular Formula	C20H31N3O5
Molecular Weight	393.48 g/mol
Synonyms	Z-Ser-Leu-NH2; Cbz-Ser-Leu-NH2; Benzyloxycarbonyl-L-seryl-L-leucinamide; Nα-Cbz-L-seryl-L-leucinamide; (2S)-2-[[(2S)-2-[[(Benzyloxy)carbonyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanamide; Z-Ser-Leu-Amide; Cbz-Ser-Leu-Amide; N-Carbobenzoxy-L-serylleucinamide
EINECS	Contact for details

Quality Control

Our n-Benzyloxycarbonylserylleucinamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.