Description

2-Nitro-1-β-D-Ribofuranosyl-1H-Imidazole is a specialized nucleoside analog, a key synthetic intermediate in medicinal chemistry and life science research. Its primary value lies in its role as a crucial precursor for the synthesis of modified nucleosides and potential pharmaceutical agents, particularly in antiviral and anticancer drug discovery. This high-purity compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing novel therapeutic compounds and biochemical probes.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used in the study of enzyme mechanisms, nucleic acid chemistry, and the development of molecular probes.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for advanced applications.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	2-Nitro-1-β-D-Ribofuranosyl-1H-Imidazole
CAS No.	17306-43-3
Molecular Formula	C8H11N3O7
Molecular Weight	261.19 g/mol
Synonyms	1-(β-D-Ribofuranosyl)-2-nitroimidazole; 2-Nitro-1-(β-D-ribofuranosyl)imidazole; 2-Nitroimidazole riboside; NSC 38297; 1H-Imidazole, 2-nitro-1-β-D-ribofuranosyl-; 2-Nitro-1-β-D-ribofuranosylimidazole; β-D-Ribofuranoside, 2-nitro-1H-imidazol-1-yl
EINECS	Contact for details

Quality Control

Our 2-Nitro-1-β-D-Ribofuranosyl-1H-Imidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.