Description

L-Phenylalanine, 4-Nitro-n-[(Phenylmethoxy)Carbonyl]- is a specialized, high-purity chemical intermediate primarily used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise building blocks for complex molecules, particularly in pharmaceutical development. Its defined stereochemistry and functional groups make it essential for applications in peptide chemistry, medicinal chemistry, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce modified phenylalanine residues with specific protecting groups.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the development of novel therapeutic agents.
• Biochemical Research: Employed in the study of enzyme inhibitors and as a precursor for labeled compounds in biochemical assays.
• Fine Chemical Production: Utilized in the multi-step synthesis of other high-value, specialized fine chemicals and advanced materials.

Basic Information

Product Name	L-Phenylalanine, 4-Nitro-n-[(Phenylmethoxy)Carbonyl]-
CAS No.	17224-90-7
Molecular Formula	C17H16N2O6
Molecular Weight	344.32 g/mol
Synonyms	N-Cbz-4-Nitro-L-phenylalanine; (S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-nitrophenyl)propanoic acid; Z-4-Nitro-L-Phe-OH; Cbz-4-Nitro-L-phenylalanine; N-[(Benzyloxy)carbonyl]-4-nitro-L-phenylalanine; 4-Nitro-N-carbobenzoxy-L-phenylalanine; Nα-Carbobenzoxy-4-nitro-L-phenylalanine
EINECS	Contact for details

Quality Control

Our L-Phenylalanine, 4-Nitro-n-[(Phenylmethoxy)Carbonyl]- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP standards where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.