Description

Cbz-1-Amino-1-Cyclopentanecarboxylic Acid CAS NO 17191-44-5 is a protected amino acid derivative, specifically a carbobenzyloxy (Cbz)-protected cyclopentane-based unnatural amino acid. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering a rigid, constrained structure to modulate biological activity and stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs and bioactive molecules.
• Peptidomimetic Research: Used to introduce conformational constraints into peptide backbones to enhance metabolic stability and receptor selectivity.
• Medicinal Chemistry: Serves as a building block in structure-activity relationship (SAR) studies for drug candidate optimization.
• Protease Inhibitor Development: Incorporated into the design of inhibitors targeting specific enzymes due to its cyclopentane scaffold.
• Chemical Biology: Employed in the synthesis of custom peptides for probing protein function and interactions.
• Academic & Industrial R&D: Fundamental research tool in organic synthesis and peptide science laboratories worldwide.

Basic Information

Product Name	Cbz-1-Amino-1-Cyclopentanecarboxylic Acid
CAS No.	17191-44-5
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	1-[(Benzyloxy)carbonylamino]cyclopentanecarboxylic Acid; (1-Aminocyclopentyl)carbamic Acid Benzyl Ester; N-Carbobenzyloxy-1-aminocyclopentanecarboxylic Acid; N-Cbz-1-Aminocyclopentanecarboxylic Acid; Z-1-Amino-1-cyclopentanecarboxylic Acid; 1-(N-Cbz-amino)cyclopentanecarboxylic Acid; 1-Amino-1-cyclopentanecarboxylic Acid N-Carbobenzyloxy Derivative; UNII-9F4K8Q4Q4M
EINECS	Contact for details

Quality Control

Our Cbz-1-Amino-1-Cyclopentanecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.