Description

n-Bromoacetazolamide is a specialized brominated derivative of the carbonic anhydrase inhibitor acetazolamide. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce bromine functionality into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of new carbonic anhydrase inhibitors with potential applications in treating glaucoma, epilepsy, and altitude sickness.
• Biochemical Research: Used as a probe or reference standard in enzymatic studies to investigate the structure-activity relationships (SAR) of sulfonamide-based inhibitors.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides or fungicides that target plant metabolic pathways.
• Fine Chemical Synthesis: Employed in organic synthesis for the introduction of the bromoacetamido moiety, enabling further functionalization in complex molecules.
• Material Science Research: Potential use in developing specialized polymers or coatings where the sulfonamide and bromine groups impart specific properties.

Basic Information

Product Name	n-Bromoacetazolamide
CAS No.	17124-38-8
Molecular Formula	C5H6BrN3O3S2
Molecular Weight	300.15 g/mol
Synonyms	2-Acetamido-1,3,4-thiadiazole-5-sulfonamide, N-Brominated; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide, N-Bromo derivative; Bromoacetazolamide; N-Bromoacetazolamide; Acetazolamide Bromo Derivative; 2-(Bromoacetamido)-1,3,4-thiadiazole-5-sulfonamide; N-Bromo-5-acetamido-1,3,4-thiadiazole-2-sulfonamide
EINECS	Contact for details

Quality Control

Our n-Bromoacetazolamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current Good Manufacturing Practices (cGMP) where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.