Description

Secretin CAS NO 17034-35-4 is a linear polypeptide hormone consisting of 27 amino acids, playing a critical role in the digestive system. It is essential for regulating gastric acid secretion and stimulating pancreatic bicarbonate output, making it a vital biochemical tool for research and diagnostic applications. This high-purity peptide is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focused on gastroenterology and endocrinology.

Application

• Gastrointestinal Research: Fundamental tool for studying gastric acid secretion, pancreatic exocrine function, and duodenal motility in preclinical models.
• Diagnostic Testing: Key component in the Secretin Stimulation Test for diagnosing pancreatic exocrine insufficiency, gastrinoma (Zollinger-Ellison syndrome), and chronic pancreatitis.
• Pharmaceutical Development: Used in the research and quality control of drugs targeting digestive disorders and hormone-related pathways.
• Biochemical Standard: Serves as a reference standard for calibrating analytical instruments and validating assay methods in clinical and research laboratories.
• Cell Signaling Studies: Investigates the role of secretin and its receptor in cellular communication and regulatory physiology.

Basic Information

Product Name	Secretin
CAS No.	17034-35-4
Molecular Formula	C130H220N44O41
Molecular Weight	3055.4 g/mol
Synonyms	Secretin (porcine); Secretin, porcine; Porcine Secretin; Gastrointestinal Peptide Hormone Secretin; HSDGTFTSELSRLREGARLQRLLQGLV; SCT; 27AA Linear Polypeptide Hormone
EINECS	Contact for details

Quality Control

Our Secretin is manufactured under strict quality management systems to ensure the highest standards of purity and biological activity. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Conforms (by in vitro assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.