Description

3-[(4S)-2,5-Dioxo-4-Imidazolidinyl]Propanoic Acid is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the preparation of complex, biologically active molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications in asymmetric synthesis and peptidomimetic drug discovery.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly those targeting protease inhibition or containing hydantoin-derived scaffolds.
• Peptidomimetics Research: Serves as a constrained amino acid analog for constructing peptide-like chains with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in stereoselective reactions to introduce chiral centers into target molecules.
• Bioconjugation Chemistry: The carboxylic acid functionality allows for coupling to other molecules, useful in creating labeled compounds or prodrugs.
• Chemical Biology Probes: Used in the development of activity-based probes and other tools for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	3-[(4S)-2,5-Dioxo-4-Imidazolidinyl]Propanoic Acid
CAS No.	17027-50-8
Molecular Formula	C6H8N2O4
Molecular Weight	172.14 g/mol
Synonyms	(S)-3-(2,5-Dioxo-4-imidazolidinyl)propanoic Acid; (S)-Hydantoin-5-propionic Acid; L-Hydantoin-5-propionic Acid; (4S)-2,5-Dioxo-4-imidazolidinepropanoic Acid; (S)-3-(2,5-Dioxoimidazolidin-4-yl)propanoic Acid; NSC 113928; (S)-HPA
EINECS	Contact for details

Quality Control

Our 3-[(4S)-2,5-Dioxo-4-Imidazolidinyl]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.