Description

Nps-Ser(Tbu)-Oh Dcha is a protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the integrity and yield of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and research sectors for the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of serine into peptide chains while protecting reactive side chains.
• Pharmaceutical Research & Development: Used in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a modified amino acid for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening.
• Biochemical Research: Utilized in studies of protein structure-function relationships and enzyme substrates.
• Custom Peptide Manufacturing: A fundamental raw material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides.

Basic Information

Item	Details
Product Name	Nps-Ser(Tbu)-Oh Dcha
CAS No.	16990-60-6
Molecular Formula	C₂₀H₃₂N₂O₆S
Molecular Weight	428.55 g/mol
Synonyms	N-2-Nitrophenylsulfenyl-O-tert-butyl-L-serine Dicyclohexylamine Salt; 2-[[(2-Nitrophenyl)sulfanyl]amino]-3-[(2-methylpropan-2-yl)oxy]propanoic acid - dicyclohexylamine (1:1); Nps-Ser(OtBu)-OH·DCHA; NPS-Ser(TBU)-OH DCHA Salt; L-Serine, N-[(2-nitrophenyl)thio]-, O-(1,1-dimethylethyl)-, compd. with N-cyclohexylcyclohexanamine (1:1); Nps-L-Ser(O-t-Bu)-OH DCHA; N-2-Nitrophenylsulfenyl-O-tert-butylserine DCHA Salt
EINECS	Contact for details

Quality Control

Our Nps-Ser(Tbu)-Oh Dcha is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards to support our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.